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methsuximide

   Also found in: Wikipedia 0.01 sec.
methsuximide /meth·sux·i·mide/ (meth-suk´sĭ-mīd) an anticonvulsant used in the treatment of seizures in absence epilepsy.
methsuximide
[methsuk′simīd]
an anticonvulsant.
indication It is prescribed in the treatment of refractory absence seizures.
contraindications Known hypersensitivity to this drug or to any succinimide prohibits its use.
adverse effects Among the more serious adverse effects are blood dyscrasias, liver and kidney damage, and systemic lupus erythematosus.

methsuximide [meth-suk´sĭ-mīd]
an anticonvulsant used in the treatment of petit mal epilepsy; administered orally.

methsuximide
(methsuk´simīd),
n brand name: Celontin;
drug class: anticonvulsant;
action: inhibits spike wave formation in absence seizures (petit mal); decreases amplitude, frequency, duration, spread of discharge in minor motor seizures;
use: refractory absence seizures (petit mal).

methsuximide
Celontin® Neurology An antiepileptic used for absence seizures/petit mal epilepsy. See Therapeutic drug monitoring.


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In contrast, first-generation AEDs that do not appear to be associated with a significant risk of birth defects include the benzodiazepines (clonazepam [Klonopin], clorazepate [Tranxene], diazepam [Valium], and lorazepam [Ativan]) and succinimides (ethosuximide [Zarontin] and methsuximide [Celontin]).
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