methenamine


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Related to methenamine: methylamine, methenamine mandelate, methenamine silver stain

methenamine

 [mĕ-the´nah-mēn]
a urinary antiseptic, administered orally as the hippurate and mandelate salts.

meth·en·a·mine

(meth-en'ă-mēn),
A condensation product obtained by the action of ammonia on formaldehyde; in acidic urine, it decomposes to yield formaldehyde, a urinary antiseptic.
Synonym(s): hexamine

methenamine

/meth·en·amine/ (meth″en-am´in) an antibacterial used in urinary tract infections; administered as the hippurate and mandelate salts.

methenamine

(mə-thē′nə-mēn′, -mĭn)
n.
An organic compound, C6H12N4, used as a urinary tract antiseptic, in the manufacture of explosives, and in rubber vulcanizing. Also called hexamethylenetetramine.

methenamine

[methē′nəmēn]
a urinary antibacterial.
indication It is prescribed in the treatment of urinary tract infections.
contraindications Liver or kidney dysfunction or known hypersensitivity to this drug or to mandelic acid prohibits its use. It should not be used by patients receiving sulfonamides.
adverse effects Among the most serious adverse effects are severe GI disturbances and rashes.

methenamine

A disinfectant once used as an oral urinary tract antiseptic; in acid urine, methenamine decomposes, generating formaldehyde, which is toxic to urinary tract bacteria.

methenamine

a white crystalline powder used orally as a urinary antiseptic; in acidic urine it is hydrolyzed to formaldehyde and ammonia. Called also hexamine.

methenamine hippurate
hexamine combined with hippuric acid.
methenamine mandelate
a salt of hexamine and mandelic acid, used in infections of the urinary tract.
References in periodicals archive ?
Rapid Grocott's methenamine silver nitrate method for fungi and Pneumocystis carinii.
1996 [41] Subjective evaluation and clinical examination of Methenamine effect on sweating rate.
Methenamine is broken down in the urine (not in serum) to ammonia and the active agent formaldehyde.
The quantities added to the urine sample corresponded to 200%, except for methenamine (100%), of the patient's daily intake of furosemide (40 mg/day), acenocoumarol (2-3 mg/day), pyridoxine (20 mg/day), tamoxifen (20 mg/day), oxazepam (10 mg/day), and methenamine (3 g/day), distributed in a 24-h portion of urine, assuming complete clearance by the urine.
methenamine is hydrolyzed to form formaldehyde, which kills the bacteria without selecting for resistance.
Histopathologic examination was conducted after the liver sections were stained with hematoxylin and eosin, periodic acid-Schiff, and Gomori methenamine silver.
Gomori methenamine silver staining, periodic acid-Schiff staining, and Ziehl-Neelsen staining were negative for infective microorganisms.
Results of the Fite acid-fast, Gram's, and Grocott methenamine silver stains were negative for bacteria and fungi.
Acid-fast bacilli, periodic acid-Schiff, and Grocott methenamine silver stains were all negative for acid-fast bacilli or fungi.
Furthermore, the effects of lisdexamfetamine may be increased by tricyclic antidepressants, monoamine oxidase inhibitors, and propoxyphene and may be decreased by chlorpromazine, haloperidol, lithium carbonate, methenamine therapy, and urinary acidifying agents (e.
The efficacy of methenamine hippurate has been demonstrated in some studies but not in others.
Special stains for acid-fast, Gomori methenamine silver, and periodic acid-fast were negative, and malignant cells were not identified.