methazolamide


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methazolamide

 [meth″ah-zo´lah-mīd]
a carbonic anhydrase inhibitor used in the treatment of glaucoma.

methazolamide

/meth·a·zo·la·mide/ (meth″ah-zo´lah-mīd) a carbonic anhydrase inhibitor used as an adjunct to reduce intraocular pressure in the treatment of glaucoma.

methazolamide

[meth′əzō′ləmīd]
a carbonic anhydrase inhibitor.
indication It is prescribed in the treatment of glaucoma.
contraindications Severe kidney or liver dysfunction, hyponatremia, hypokalemia, Addison's disease, severe pulmonary obstruction, adrenocortical insufficiency, marked kidney or liver dysfunction, or known hypersensitivity to this drug or many other sulfonamides prohibits its use.
adverse effects Among the more serious adverse effects are malaise, aplastic anemia, drowsiness, paresthesia, hypersensitivity reactions, and acidosis.

methazolamide

(meth´əzō´ləmīd´),
n brand name: Neptazane;
drug class: carbonic anhydrase inhibitor;
action: decreases production of aqueous humor in the eye, which lowers intraocular pressure;
uses: open-angle glaucoma or preoperatively in narrow-angle glaucoma.
methemoglobinemia
(met´hēməglō´binē´mēə),
n an ab-normality of hemoglobin in which the iron is in the ferric state as a result of exposure to industrial substances or the ingestion of toxic agents such as phenacetin, sulfonamides, aniline nitrates, or nitrates. A rare congenital form is seen most commonly in persons with Greek heritage. Symptoms include generalized cyanosis, headache, drowsiness, and confusion. Methemoglobin does not carry oxygen. This condition has recently been associated with topical benzocaine spray when applied to the oropharynx.
methenamine salts
(məthē´nəmēn´),
n brand names: Hiprex, Urex;
drug class: urinary antiinfective;
action: in acid urine, it is hydrolyzed to ammonia and formaldehyde, which are bactericidal;
uses: prophylaxis and treatment of uncomplicated urinary tract infections.

methazolamide

a carbonic anhydrase inhibitor used orally in the treatment of glaucoma.
References in periodicals archive ?
Miscellaneous medications: clofibrate, dichlorphenamide, fenfluramine, ketoconazole, methadone, methazolamide, norethindrone, thiabendazole
The company also introduced generic versions of the diuretic methazolamide and of Lederle's ocular drug Neptazane (methazolamide) which is used to treat various forms of glaucoma.
NEW YORK -- Fera Pharmaceuticals is pleased to announce availability of Methazolamide Tablets and plans to commence shipping June 1, 2012.
Long-term administration of methazolamide is contraindicated in patients with angle-closure glaucoma, since organic closure of the angle may occur in spite of lowered intraocular pressure.
Caution is advised for patients receiving highdose aspirin and methazolamide concomitantly, as anorexia, tachypnea, lethargy, coma, and death have been reported with concomitant use of highdose aspirin and carbonic anhydrase inhibitors.