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methanesulfonic acid

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meth·ane·sul·fon·ic acid (mthn-sl-fnk)
n.
A liquid soluble in water, alcohol, and ether used as a reaction catalyst.


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Select C(alpha), O-oximes, such as 3,4-dimethoxyacetophenone or 3,4- dimethylacetophenone oxime, were dilithiated in excess LDA, followed by condensation with ethyl oxanilates to afford C-acylated intermediates that can be cyclized directly with dilute hydrochloric acid/THF, or isolated and separately acid-cyclized to 5- isoxazolecarboxamides using methanesulfonic acid and a water trap.
The test agents, whose primary mechanisms are denoted, included a methylating agent [methyl ester methanesulfonic acid (MMS)]; DNA cross-linking agents (mitomycin C and cisplatin); DNA adduct inducers [benzo[aJpyrene diolepoxide (BPDE)] and 4-nitroquinoline oxide); freeradical generators [bleomycin and hydrogen peroxide ([H.
 
 
 
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