20) This prospective standardized evaluation included full PFTs, chest HRCT, methacholine challenge
testing (MCT), and fiberoptic bronchoscopy with BAL.
In one small study of asthmatic patients receiving propranolol, there was no effect on methacholine challenge
response, histamine responsiveness, or asthma control questionnaire results.
Steroids don't affect methacholine challenge
Feasibility of shortened methacholine challenge
in preschool children.
tests were conducted between 1984 and 2000 using procedures adapted from Chatham et al.
Value of a negative aeroallergen skin-prick test result in the diagnosis of asthma in young adults: Correlative study methacholine challenge
A positive response to any of the four questions on the survey has a sensitivity of 75% and a specificity of 80% for asthma symptoms on the basis of a clinical examination with immunoglobulin E testing against common allergens, spirometry, and methacholine challenge
Airway hyper responsiveness was documented by a positive methacholine challenge
To define airway hyperresponsiveness, the study used a standard criterion: methacholine challenge
cutoff of less than 8 mg/mL for causing a 20% fall in [FEV.
Of the 206 subjects who had a methacholine challenge
, 16% (32) demonstrated BHR.
History and laryngoscopy ruled out asthma in half (13) of the patients mistakenly diagnosed with it; methacholine challenge
testing excluded the other half.
Primary Outcome Measures: Methacholine challenge
test, a variety of pulmonary function tests, subjective quality of life scores, C-reactive protein (CRP), and exhaled nitric oxide (NO)