Metenkephalin | definition of metenkephalin by Medical dictionary
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Pentapeptide endorphins, found in many parts of the brain, that bind to specific receptor sites, some of which may be pain-related opiate receptors; hypothesized as endogenous neurotransmitters and nonaddicting analgesics. Metenkephalin is Tyr-Gly-Gly-Phe-Met; leuenkephalin has Leu in place of Met; proenkephalin has Pro in place of Met.
metenkephalin One of the several ENDOGENOUS opium-like substances having a sequence of five amino acids. See also ENDORPHINS.
References in periodicals archive
This project will determine the effect of metenkephalin
, Tyr-Gly-Gly (YGG) and Tyr-Gly (YG) on the in vitro production of the cytokine, IL-2.
Because of its exopeptidase activity, it has been implicated in the metabolism of metenkephalin
(18) and angiotensin (Ang) III (17); its endopeptidase activity is also thought to be involved in neurotensin metabolism (19).