metastatic (redirected from metastatic cascade)

Metastatic

The term used to describe a secondary cancer, or one that has spread from one area of the body to another.

Mentioned in: Coagulation Disorders

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metastatic.

See metastasis.

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metastatic

pertaining to or of the nature of a metastasis.

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metastatic abscesses

abscesses seeded down in tissues distant from a mother abscess.

metastatic calcification

deposition of calcification in soft tissues, e.g. muscles and connective tissue.

metastatic cascade

the series of events leading to metastasis, starting with detachment of neoplastic cells from the primary site through to attachment and tumor growth at a distant site.

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brain tumor

Neurology A neoplasm affecting the brain which may be 1º–brain or meninges, or 2º–ie metastatic to the brain; malignant gliomas account for 2.5% of all cancer-related deaths; BTs are the 3^rd most common CA in ages 15-34; 35,000 BTs occur/yr–US; 1^st-degree relatives of children with brain tumors have a 5-fold ↑ in the risk of CNS tumors, leukemia, and other childhood tumors in the affected family Clinical Seizures, vision or hearing loss, hemiparesis, double vision, headache, weird behavior, N&V, memory loss Imaging MRI without and with contrast, CT Management Surgery, gamma knife radiotherapy are often effective; chemotherapy, immunotherapy are not. Cf Gamma knife

Brain tumors/masses

Primary

Nonneoplastic

Craniopharyngioma, colloid cysts

Primary–benign

Meningioma, pituitary adenoma, acoustic neuroma, epidermoid tumors, choroid plexus papilloma

Primary–low grade

Pilocytic astrocytoma, astrocytoma, hemangioblastoma, oligodendroglioma, ganglioglioma

Primary–malignant

Anaplastic astrocytoma, glioblastoma multiforme, ependymoma, lymphoma, medulloblastoma, primitive neuroectodermal tumor, germ cell tumor, pineal cell tumor, chordoma, choroid plexus carcinoma

Metastatic

Carcinoma, meningeal carcinomatosis

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