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Relating to metastasis.


brain tumor

Neurology A neoplasm affecting the brain which may be 1º–brain or meninges, or 2º–ie metastatic to the brain; malignant gliomas account for 2.5% of all cancer-related deaths; BTs are the 3rd most common CA in ages 15-34; 35,000 BTs occur/yr–US; 1st-degree relatives of children with brain tumors have a 5-fold ↑ in the risk of CNS tumors, leukemia, and other childhood tumors in the affected family Clinical Seizures, vision or hearing loss, hemiparesis, double vision, headache, weird behavior, N&V, memory loss Imaging MRI without and with contrast, CT Management Surgery, gamma knife radiotherapy are often effective; chemotherapy, immunotherapy are not. See Gamma knife.
Brain tumors/masses
Craniopharyngioma, colloid cysts
Meningioma, pituitary adenoma, acoustic neuroma, epidermoid tumors, choroid plexus papilloma
Primary–low grade
Pilocytic astrocytoma, astrocytoma, hemangioblastoma, oligodendroglioma, ganglioglioma
Anaplastic astrocytoma, glioblastoma multiforme, ependymoma, lymphoma, medulloblastoma, primitive neuroectodermal tumor, germ cell tumor, pineal cell tumor, chordoma, choroid plexus carcinoma
Carcinoma, meningeal carcinomatosis


Relating to metastasis.


(mĕ-tăs′tă-sis) plural.metastases [″ + stasis, stand]
1. Movement of bacteria or body cells (esp. cancer cells) from one part of the body to another.
Enlarge picture
METASTASES: CT scan of liver (upper left) with round metastatic tumors (Courtesy of Harvey Hatch, MD, Curry General Hospital)
2. Change in location of a disease or of its manifestations or transfer from one organ or part to another not directly connected. See: illustration

The usual application is to the manifestation of a malignancy as a secondary growth arising from the primary growth in a new location. The malignant cells may spread through the lymphatic circulation, the bloodstream, or avenues such as the cerebrospinal fluid.

metastatic (mĕt″ă-stăt′ĭk), adjective


The term used to describe a secondary cancer, or one that has spread from one area of the body to another.
Mentioned in: Coagulation Disorders


pertaining to or of the nature of a metastasis.

metastatic abscesses
abscesses seeded down in tissues distant from a mother abscess.
metastatic calcification
deposition of calcification in soft tissues, e.g. muscles and connective tissue.
metastatic cascade
the series of events leading to metastasis, starting with detachment of neoplastic cells from the primary site through to attachment and tumor growth at a distant site.
References in periodicals archive ?
The atypical aspect of this case is that our patient was a female nonsmoker with a relatively small laryngeal tumor who developed late metastatic dissemination to the brain, lungs, and pelvis.
The NM23 mRNA levels were found to decline in tumors from women with many involved lymph nodes, an indicator of high metastatic potential," she says.
In such a case, it is possible that the neck mass itself is the primary tumor or that the neck mass represents a metastatic deposit with spontaneous regression of the primary elsewhere; only four such cases have been described.
Expression was greater in the metastatic lymph nodes than in the primary tumors, as evidenced by the greater intensity of immunofluorescence staining of EphB4 in the lymph nodes.
Findings on frozen-section analysis were consistent with a metastatic sarcoma.
1-3) In contrast, the literature contains only 26 cases of renal cell carcinoma metastatic to the nose and only eight cases metastatic to the tongue.
2) In rare but clearly documented cases, some metastatic lesions were cutaneously implanted following percutaneous transhepatic biliary drainage.