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metaplasia

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metaplasia /meta·pla·sia/ (met″ah-pla´zhah) the change in the type of adult cells in a tissue to a form abnormal for that tissue.metaplas´tic
myeloid metaplasia  a syndrome characterized by myeloid tissue in extramedullary sites with nucleated erythrocytes and immature granulocytes in the circulating blood and extramedullary hematopoiesis in the liver and spleen, as well as anemia and splenomegaly. Both a primary form (agnogenic myeloid m.) and forms secondary to carcinoma, leukemia, leukoerythroblastosis, and tuberculosis are known.

met·a·pla·sia (mt-plzh)
n.
1. Normal transformation of tissue from one type to another, as in the ossification of cartilage to form bone.
2. Transformation of cells from a normal to an abnormal state.

metaplasia
[met′əplā′zhə]
the reversible conversion of normal tissue cells into another, less differentiated cell type in response to chronic stress or injury. With prolonged exposure to the inducing stimulus, cancerous transformation can occur.

metaplasia [met″ah-pla´zhah]
the change in the type of adult cells in a tissue to a form abnormal for that tissue. adj., adj metaplas´tic.
agnogenic myeloid metaplasia the primary or idiopathic form of myeloid metaplasia, which is often accompanied by myelofibrosis; it is considered one of the myeloproliferative disorders. Called also aleukemic or nonleukemic myelosis.
myeloid metaplasia the occurrence of myeloid tissue in extramedullary sites; specifically, a syndrome characterized by splenomegaly, anemia, nucleated erythrocytes and immature granulocytes in the circulating blood, and extramedullary hematopoiesis in the liver and spleen. The primary form is called agnogenic myeloid metaplasia. The secondary or symptomatic form may be associated with various diseases, including carcinomatosis, tuberculosis, leukemia, and polycythemia vera.

metaplasia (meˈ·t·plāˑ·zhē·),
n abnormal cell growth in which cells become unlike the normal cells in the tissue of which they are a part.

metaplasia (met´plā´zh),
n a change in the type of adult cells in a tissue to a form that is not normal for that tissue.

metaplasia
the change in the type of adult cells in a tissue to a form abnormal for that tissue.

Patient discussion about metaplasia.

Q. what is fragments of endocervical glandular mucosa with inflammation and squamous metaplasia fragments of endocervical glandular mucosa

A. It means that part of the mucose on the cervix area has changes from a certain kind of mucose cells to another, and that there is a bit of an inflammation around it. This should be brought to the knowledge of a gynecologist and be monitored by him/her.

Q. what is metaplasia i had 2 surgeries in my left breast for some cyst they found metaplasia in the biopsy

A. from what i remember while reading on the subject- cells can go through different changes. one of them is metaplasia- change of form. our body is amazingly flexible, and under stress cells can change form and function. like if you have continues heartburns, cells in your esophagus will change to cells similar to the stomach and start excreting anti acid materials. finding that on a biopsy means the cells in the cyst changed function.

Read more or ask a question about metaplasia


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Dr Whitsett and his team at Cincinnatti Children's team Hospital found "good" lung cells called Clara cells change into mucus cells in a process called metaplasia - and that the process could be reversed.
We present a case of postoperative osseous metaplasia in the maxillary sinus that led to the formation of mature bone with a well-developed haversian system and bone marrow.
With the sitagliptin alone, however, the rats had abnormally high rates of cell production in their pancreatic ducts; a few developed an abnormality known as ductal metaplasia, and one developed pancreatitis.
 
 
 
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