metalloproteinase


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me·tal·lo·pro·tein·ase

(met'a-lō-prō'tēn-āz),
A family of protein-hydrolyzing endopeptidases that contain zinc ions as part of the active structure.

me·tal·lo·pro·tein·ase

(mĕ-tal'ō-prō'tēn-ās)
A family of protein-hydrolyzing endopeptidases that contain zinc ions as part of the active structure.
References in periodicals archive ?
Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP1) by colorectal cancer cells and adjacent stroma cells-associations with histopathology and patients outcome.
The catalytic domain of human membrane type-1 matrix metalloproteinase (MMP) will be used as model enzyme.
Glucosamine can complement ectogenous glucosaminoglycan, provide the precursor of disaccharide unit needed in the synthsis of glycosaminoglycan inside the body, and stimulate synthesis of proteoglycan and collagen in the chondrocyte, as well as complement lost ingredients of cartilage matrix and inhibit the expression of matrix metalloproteinase so as to maintain the normal metabolism of cartilage matrix and accelerate the recovery of cartilage.
s NephroCheck Test to obtain measurements of the two biomarkers, tissue inhibitor of metalloproteinase 2 (TIM P-2) and insulin-like growth factor binding protein 7 (IGFBP-7).
Artesunate significantly suppressed cigarette smoke-induced pulmonary gene expression of TNF-[alpha], MIP-2[alpha], TGF-[beta], metalloproteinase (MMP)-9 and tissue inhibitor of metalloproteinase (TIMP)-1 (Fig.
Another theory is based around abnormal expression of matrix metalloproteinase (MMP)--a generic name for a group of enzymes that can degrade part of the structure of the extracellular matrix.
The UVA1 also caused the skin to darken a little with each exposure, but this tan didn't protect against further production of the collagen-destroying molecule, called matrix metalloproteinase 1 or MMP1, when the skin was exposed to more doses of UVA1.
We also found that curcumin, CCL2 and PMA, in part, function through the differential regulation of the proteolytic protein matrix metalloproteinase (MMP)-9.
2002) "Infrared-A radiation-induced matrix metalloproteinase I expression is mediated through extracellular signal regulated kinase 1/2 activation in human dermal fibroblasts.
Irit Sagi of the Biological Regulation Department and her research group have spent years looking for ways to home in on and block members of the matrix metalloproteinase (MMP) enzyme family.
Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor.

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