mesothelioma panel

mesothelioma panel

A panel of immune markers used to confirm or exclude a mesothelioma, which may be histologically mistaken for an adenocarcinoma.

Mesothelioma panel
Mesothelioma
+ve—CK5/6, calretinin, thrombomodulin, WT-1, D2-40, EMA (membrane and cytoplasmic).
-ve—BerEP4, MOC-31, TTF-1.

Reactive mesothelial cells
+ve—CK 5/6, calretinin, desmin.
-ve—e-cadherin, EMA, p53.
References in periodicals archive ?
Similarly, none of 23 benign cases stained by the French Mesothelioma Panel had loss of BAP1.
11-12) Since the late 1990s, the International Mesothelioma Panel has been headed by Francoise Galateau-Salle, MD, of Caen, France, who is also chair of the French Mesothelioma Reference Panel.
The International Mesothelioma Panel recommends that at least 2 mesothelial and 2 carcinoma markers be used in addition to a pancytokeratin.