mesoridazine


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mesoridazine

 [mes″o-rid´ah-zēn]
a phenothiazine used in the form of the besylate salt as an antipsychotic agent.

mesoridazine

/meso·rid·a·zine/ (mes″o-rid´ah-zēn) a phenothiazineantipsychotic, used as the besylate salt.

mesoridazine

[mez′ərid′əzēn]
a phenothiazine antipsychotic.
indication It is prescribed in the treatment of schizophrenia.
contraindications Parkinson's disease, concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to other phenothiazine medications prohibits its use.
adverse effects Among the more serious adverse effects are prolongation of the QT interval (increases risk of torsades de pointes arrhythmia), hypotension, liver toxicity, a variety of extrapyramidal reactions, persistent tardive dyskinesia, blood dyscrasias, and hypersensitivity reactions.
References in periodicals archive ?
5-10 mg Medium Potency Trifluoperazine Stelazine 1-10 mg Typical Perphenazine Trilafon 2-16 mg Thiothixene Navane 2-20 mg Loxapine Loxitane 5-50 mg Low Potency Molindone Moban 5-100 mg Typical Mesoridazine Serentil 10-100 mg Thioridazine Mellaril 10-200 mg Chlorpromazine Thorazine 10-200 mg Adapted from Wilens (1999) and Li, Pearrow, & Jimerson (2010).
Furthermore, several drugs may produce false positive results for phencyclidine including ketamine, dextromethorphan, diphenhydramine, ibuprofen, imipramine, meperidine, mesoridazine, thioridazine, and venlafaxine (Sena, Kazimi & Wu 2002).
Currently available drugs associated with QT prolongation include most anti-dysthythmics, erythromycin, droperidol, mesoridazine, and methadone.
Due to the potential additive effect of ziprasidone and other drugs that prolong the QT interval, ziprasidone should not be given with dofetilide, sotalol, quinidine, class IA or class III antiarrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, pimozide, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, or tacrolimus.
In the study, the category of conventional antipsychotics included perphenazine, fluphenazine, trifluoperazine, thiothixene, haloperidol, molindone, loxapine, prochlorperazine, acetophenazine, promazine, triflupromazine, thioridazine, mesoridazine and chlorprothixene.
None of the patients was receiving dextromethorphan, diphenhydramine, ibuprofen, imipramine, meperidine, mesoridazine, or thioridazine--drugs known to produce false-positive results with other PCP immunoassays.
Among antipsychotics, clozapine and mesoridazine demonstrated a low carcinogenicity risk in preclinical studies, while risperidone, olanzapine, quetiapine, aripiprazole, and to a slightly lesser degree, ziprasidone demonstrated a high risk.
2] vapor and 366 nm light 20 Mesoridazine S5 Mandelin, pink color 20 Methampetmine S1 366 nm, fluorescence quench 30 Morphine S4 Marquis, purple color 40 Nortriptyline S4 Marquis, red-brown color 20 Phencyclidine S3 D1, visual observation 200 Phencyclidine S6 D2, visual observation 100 (a) Analtech no.