Sclerosing mesenteritis is a rare pathologic diagnosis characterized by inflammation of the mesentery that should be considered in CT evaluation of a patient with a soft tissue abdominal mass while ensuring appropriate work-up to rule out diagnoses that may have a similar appearance with a worse prognosis.
Malignant fibromatous peritoneal mesothelioma associated with liposclerotic mesenteritis.
CT findings in sclerosing mesenteritis (panniculitis): Spectrum of disease.
F-18 FDG PET demonstration of sclerosing mesenteritis.
Myriad CT presentations have been described for sclerosing mesenteritis.
Other entities that must be differentiated from sclerosing mesenteritis are inflammatory pseudotumor and lipogenic liposarcoma.
The fat-ring sign in cases of panniculitis has been described to aid in differentiating sclerosing mesenteritis from other entities.
Another finding that may be observed in sclerosing mesenteritis is the presence of a pseudocapsule surrounding the affected mesentery, seen as a soft tissue density band.
Finally, when fibrosis becomes the main feature, the terms sclerosing or retractile mesenteritis have been applied.
The etiology of sclerosing mesenteritis remains unknown.
The most important goal in managing patients with sclerosing mesenteritis is to exclude the possibility of malignancy, particularly when the clinical presentation is a single, large, intra-abdominal mass.
It is generally agreed that the proper treatment for sclerosing mesenteritis should be based on the stage of the disease.