Preliminary experiments in our laboratory suggest an exciting possibility--that stem cells from hair follicles may be similar to bone-marrow mesenchymal cells
," Andreadis underscores.
The authors exposed mouse mesenchymal cells
to lead in vitro and observed signaling changes in several proteins active in chondrogenesis: transforming growth factor-beta (TGF-[beta]), bone morphogenetic protein (BMP), activating protein 1 (AP-1), and nuclear factor kappa B (NF[kappa]B).
This curious delay coincides with the time that it takes mesenchymal cells
to arrive at a fracture site.
Thus, for those wishing to generate lots of mesenchymal cells
, our cells could [be the answer.
2010), as well omental progenitor or non-progenitor mesenchymal cells
(GOMEZ-GIL et al.
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells
in children with osteogenesis imperfecta.
Similar experiments using hydrogel seeded with bone marrow-derived mesenchymal cells
also showed vascular growth, but without the guarantee of a tissue match, Jacot said.
SFT has been recently considered to originate from the mesenchymal cells
of the submesothelial connective tissue of the pleura.
Wnt/[beta]-catenin signaling plays significant roles in both embryonic development and tumorigenesis, and when activated induces differentiation of mesenchymal cells
with pluripotential into osteoblast progenitors to become osteoblasts.
Adherent marrow--derived mesenchymal cells
were shown to have similar fibroblastic morphology, while others were found to be round with dark centers and transparent peripheries.
This rich source contains a much higher concentration of mesenchymal cells
than bone marrow (95 percent compared to 25-50 percent).