mercapturic acid


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Related to mercapturic acid: glucuronide, NAPQI

mer·cap·tu·ric ac·id

(mer-kap-tyūr'ik as'id),
A condensation product of l-cysteine with aromatic compounds, such as bromobenzene, and usually acetylated; formed biologically via glutathione in the liver and excreted in the urine; an S-substituted N-acetylated l-cysteine. Compare: mercapturic acid pathway.

mer·cap·tu·ric ac·id

(mĕr-kap'tyūr-ik as'id)
A condensation product of l-cysteine with aromatic compounds, such as bromobenzene; formed in the liver and excreted in the urine.
References in periodicals archive ?
Biosynthesis of mercapturic acids from allyl alcohol, allyl esters and acrolein.
Biotransformation of acrolein in rat: excretion of mercapturic acids after inhalation and intraperitoneal injection.
Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and W,W-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.
The CDC has measured the hemoglobin adducts of acrylamide and its metabolite glycidamide (CDC 2009) and plans to measure urinary mercapturic acid metabolites of acrylamide and glycidamide in NHANES participants (Alwis et al.
At present, the CDC plans to perform benzene biomonitoring in NHANES by measuring urinary mercapturic acid metabolites (Alwis et al.
Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.
To a minor extent, StO is conjugated with glutathione by glutathione S-transferases (GSTs), resulting in subsequent formation of phenyl hydroxyethyl mercapturic acids (PHEMAs), excreted in urine.
Polymorphism of xenobiotic-metabolizing enzymes and excretion of styrene-specific mercapturic acids.