mephenesin


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mephenesin (mefen´isin),

n an antispasmodic drug, 3 ortho-toloxyl, 2 propanediol. Used for the preparation of apprehensive patients for dental and periodontal procedures because of its ability to produce muscular relaxation and euphoria. Usual dosage for an adult is 1 gm in either tablet or elixir form, 20 minutes before the dental procedure.

mephenesin

a centrally acting muscle relaxant. Once used in association with pentobarbital for anesthesia, but no longer used because of its many side-effects, including venous thrombosis and hemolysis.
References in periodicals archive ?
Tenders are invited for Gel Of Mephenesin With Capsicum,Oleoresion And Nic.
Working on ways to preserve penicillin, Berger found that one of his compounds, mephenesin, had muscle-relaxant properties.
Despite aggressive treatment including breath-holding to interrupt the respiratory rhythm, continuous positive airway pressure, and medication with metoclopramine, prochlorperazine, chlorpromazine, haloperidol, mephenesin, diphenylhydantoin, baclofen, and phenobarbital, the hiccups persisted for 7 days.
Meyer HJ, Kretzschmar R (1966) Kawa pyrones: a new group of components in central muscle relaxing agents of the mephenesin type.
But a post-race drug test returned positive for the little-known drug mephenesin.
Jockey Club senior vet Keith Watkins confirmed that the drug used to dope Whytellyou was mephenesin, a muscle relaxant not commercially available in Hong Kong and which can, in some cases, cause death.
Whytellyou tested positive to the muscle relaxant, mephenesin, a prohibited substance.