They also collected samples from a second, smaller group of 87 women who presented to the hospital with premature membrane rupture
Sparks will use the money to fund pioneering research into treatment for fetal membrane rupture
, which causes 40 percent of premature births.
Inclusion criteria for the PPROM patients were as follows: pregnant women with 28-36+6 weeks of gestation, membrane rupture
within 12 h, no use of any antibiotics within 2 months, and no history of any basic diseases (such as diabetes, cardiovascular disease, and hypertension).
Oligohidroamniosis developed in the intrauterine thirty third week and early membrane rupture
occurred and the patient was hospitalized in newborn intensive care unit after intubating due to superficial respiration.
As the interval between membrane rupture
and the onset of labour extends beyond 24 hours, the risk of maternal chorioamnionitis increases 5-fold relative to women with a latency period of less than 24 hours.
For the other 18 pregnant women, with rupture of membranes before delivery, the median duration of membrane rupture
was 72h (1h to 42 days).
3) Previous studies have shown this sexually transmitted infection is associated with premature membrane rupture
, preterm labor, low birth weight, increased risk for pelvic inflammatory disease, and an increased risk for human immunodeficiency virus (HIV) transmission and acquisition in both men and women.
1 The cause, of membrane rupture
, in most cases is unknown but recent evidence suggests that infection is a major cause.
As long as maternal and fetal status are reassuring, the statement says, cesarean deliveries for failed induction of labor in the latent phase can be avoided by allowing longer durations of the latent phase (up to 24 hours) and by requiring that oxytocin be administered for 12-18 hours after membrane rupture
before deeming induction a failure.
The risk of fetal and maternal infection is known to be increased with increasing duration between membrane rupture
This study, in particular, was subject to "survivor bias," as reflected in the significantly different intervals between membrane rupture
and delivery in the two groups.
Following membrane rupture
the preterm fetus is at risk of a number of complications such as prematurity placental abruption ascending infection intrapartum fetal distress and cord prolapsed.