melorheostosis

melorheostosis

 [mel″o-re″os-to´sis]
a form of osteosclerosis, with linear tracks extending through the long bones.

mel·o·rhe·os·to·sis

(mel'ō-rē'os-tō'sis), [MIM*155950] Although the diagraph rh occurring at the beginning of a syllable in a word of Greek origin is ordinarily changed to rrh when a prefix or other lexical element is placed before it, the r is not doubled in this word.
Rheostosis confined to the long bones.
[G. melos, limb, + rheos, stream, + osteon, bone, + -ōsis]

melorheostosis

/melo·rhe·os·to·sis/ (mel″ŏ-re″os-to´sis) a form of osteosclerosis, with linear tracks extending through a long bone; see rheostosis.

melorheostosis

An idiopathic defect of long bone growth, characterised by cortical thickening of long (tubular) bones which, when stripped of muscle, simulates a candle with wax melted down a side.
 
Clinical findings
Pain, limitation of movement; contraction and/or fusion of joint spaces, usually of one limb.

melorheostosis

Lèri's disease An idiopathic defect of long bone growth, characterized by cortical thickening of long–tubular bones which, when stripped of muscle, simulates a candle with wax dribbled down a side Clinical Pain, limitation of movement, contraction and/or fusion of joint spaces, usually of one limb

mel·o·rhe·os·to·sis

(mel'ō-rē-os-tō'sis)
Rheostosis confined to the long bones.
[G. melos, limb, + rheos, stream, + osteon, bone, + -ōsis]

melorheostosis

; ivory bone formation rare hyperostosis of long bones of limbs, characterized by patchy linear sclerosis and cortical new bone formation

melorheostosis

a form of osteosclerosis, with linear tracks extending through the long bones.
References in periodicals archive ?
The other deferred microscope slide review required correlation with radiographic imaging to rule out melorheostosis.
Increased bone density without modifcation of bone shape Osteopetrosis precocious type Generalised AR delayed type Type 1 uniform AD intermediate type Type 2 endobones with renal tubular Generalised AR AR acidosis Similar other types Axial osteosclerosis osteomesopyknosis Focal sclerosis AD AR with bamboo hair in vertebrae/pelvis Pycnodysostosis Generalised AR Osteosclerosis Cortical AD Stanesu type thickening of long bones, defcient facial sinus development Osteopathia striata Radiodense SP XLD isolated with striations on all cranial sclerosis bones with cranial sclerosis Sponastrime Striated AR dysplasia metaphysis Melorheostosis Flowing SP hyperostosis Osteopoikilosis Radiodense spots AD Mixed sclerosing Combined pattern SP bone dysplasia 2.
Loss of function mutations of the LEMD3 (MAN1) gene were shown to underlie disorders characterized by increased bone density, namely osteopoikilosis, Buschke-Ollendorff syndrome (BOS), and melorheostosis (9,10).
Various developmental malformations have been reported to be associated with osteopoikilosis, including: coarctation of the aorta, double ureter, pubertas praecox, urogenital defects, growth abnormalities, peptic ulcer, diabetes mellitus at the endodermal strata level; arthritis, exostoses, osteitis condensans ilii, Klippel-Feil Syndrome, melorheostosis, spinal stenosis, cervical myelopathy, dacryocystitis, giant cell tumor, fibrous dysplasia, chondrosarcoma, osteosarcoma, synovial chondromatosis at the mesodermal level; facial abnormalities, hare lip, dental abnormalities, dermatofibrosis lenticularis disseminata, keloid formation, plantar and palmar keratomas at the ectodermal level (14-16).
Radiologically, the differential diagnosis of OPK includes osteopathia striata, melorheostosis, tuberous sclerosis, sclerotic bone metastases, and osteoma (which may have similar clinical pictures but for which medical and orthopedic treatment may be necessary).
A combination of melorheostosis, OPK, and osteopathia striata (type I) is the most frequent among the other overlap syndromes.