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an antiprotozoal agent effective against trypanosomes.
melarsoprolAn older arsenical used to treat trypanosomiasis caused by Trypanosoma cruzi (Chagas disease) and T brucei gambiense (which causes 95% of cases of sleeping sickness).
Arsenic poisoning, convulsions, loss of consciousness, rash, fever, nausea, vomiting, bloody stool; treatment-related fatalities are not uncommon. Pentamidine is the drug of choice for first-stage T brucei gambiense infection. Other agents (suramin, eflornithine and nifurtimox) are available in the US from the Centers for Disease Control and Prevention (CDC).
melarsoprolA combination of melarsan oxide and dimercaprol used to treat TRYPANOSOMIASIS. The drug is highly effective but must be used with caution because of sometimes dangerous side effects including the JARISCH-HERXHEIMER REACTION. The drug is on the WHO official list.
an antiprotozoal effective against Trypanosoma spp.