melanosome


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melanosome

 [mel´ah-no-sōm″]
any of the granules that contain melanin. The melanin is synthesized within melanocytes; then the melanosomes are transferred to keratinocytes.

mel·a·no·some

(mel'ă-nō-sōm'),
The generally oval pigment granule (0.2 by 0.6 mcm) produced by melanocytes.
Synonym(s): eumelanosome
[melano- + G. sōma, body]

melanosome

/mel·a·no·some/ (mel´ah-no-sōm″) any of the granules within the melanocytes that contain tyrosinase and synthesizes melanin; they are transferred from the melanocytes to keratinocytes.

melanosome

[mel′ənōsōm′]
one of the oval pigment granules within melanocytes that synthesize melanin.

melanosome

A large (500-nm) lysosome-related pigment-containing organelle, which provides tissues with colour and photoprotection. They are the site of synthesis, storage and transport of melanin pigments and are synthesised in skin melanocytes, in choroidal melanocytes and in retinal pigment epithelial cells in the eye of mammals.

mel·a·no·some

(mel'ă-nō-sōm)
The generally oval pigment granule (0.2 by 0.6 mcm) produced by melanocytes.
[melano- + G. sōma, body]

melanosome

oval pigmented granule produced by specialized Golgi apparatus of melanocytes; granules are transferred via melanocyte dendrites into local keratinocytes, causing skin and hair pigmentation (racial differences in skin colour relate to melanocyte activity, not to melanocyte numbers); melanosomes are concentrated over superior pole of nucleus within keratinocytes, to protect nuclear DNA from harmful effects of ultraviolet irradiation

melanosome

any of the granules that contain melanin. The melanin is synthesized within melanocytes, then the melanosomes are transferred to keratinocytes.
References in periodicals archive ?
The evolution of diverse melanosomes in these organisms raises the possibility that melanosome shape and size could yield insights into dinosaur physiology.
Mutations in a host of genes have been described that result in the failure of protein delivery to the melanosome.
Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible.
Quantifying Melanosomes in the Keratinized Layer of the Skin of Painted Turtles Reared on Light and Dark Backgrounds.
These proteins reduce melanin by blocking the transference of melanosomes to keratinocytes.
To determine the melanosome's colour, Akron researchers Matthew Shawkey and Liliana D'Alba statistically compared Archaeopteryx's melanosomes with those found in 87 species of living birds, representing four feather classes: black, gray, brown, and a type found in penguins.
Third place: "Quantitative and Qualitative Analysis of Melanosome Degradation and Processing by Epidermal Keratinocytes of Distinct Racial Sources.
122,127,128) Melanosome biogenesis involves 4 stages.
Actiwhite is a novel skin lightener with a demonstrated innovative pathway of melanin synthesis inhibition--linked to a decrease of tyrosinase activity in melanocytes and also to an inhibition of melanosome maturation--resulting in an enhanced lightening efficacy vs market benchmarks, while ensuring a perfect skin tolerance.
1,3,5-12] In addition, this study expands and further characterizes, overall and based on cell type, the melanosome and melanoma and smooth muscle immunophenotype and ultrastructural features of renal angiomyolipoma.
Actiwhite's high capacity to decrease melanogenesis is linked to a decrease of tyrosinase activity in melanocytes and also to an inhibition of melanosome maturation.