MC5R

(redirected from melanocortin-5 receptor)

MC5R

A gene on chromosome 18p11.2 that encodes a receptor for alpha, beta and gamma melanocyte stimulating hormone (MSH), the activity of which is mediated by G protein-activated adenylate cyclase. MC5R is thought to mediate the immunomodulatory properties of melanocortins and may play a role in sebum production.
References in periodicals archive ?
Chen identified the first selective antagonist of the melanocortin-5 receptor, and discovered numerous agonists and antagonists for the melanocortin-4 receptor for eating disorders.

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