megalencephaly


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megalencephaly

 [meg″ah-len-sef´ah-le]
macrencephalia; hypertrophy of the brain.

megalencephaly

(mĕg′əl-ĕn′sĕf′ə-lē) or

megaloencephaly

(mĕg′ə-lō-ĕn-)
n.
Abnormal largeness of the brain.

meg′al·en′ce·phal′ic (-ĕn′sə-făl′ĭk), meg′al·en′ce·phal′ous (-əs) adj.

megalencephaly

[meg′əlensef′əlē]
Etymology: Gk, megas + enkephalos, brain
a condition characterized by pathological parenchymal overgrowth of the brain. In some cases generalized cerebral hyperplasia is associated with mental retardation or a brain disorder, such as epilepsy. Also called macrencephaly. megalencephalic, megalencephalous, adj.

megalencephaly

A rare condition defined as a brain that weighs significantly more than the average for an infant’s age and sex, which is invariably accompanied by macrocephaly with an enlarged cranial vault due to separation of the cranial sutures.

megalencephaly

Neonatology Big-brained

megalencephaly

macrencephalia; hypertrophy of the brain.
References in periodicals archive ?
Hemimegalencephaly is unilateral megalencephaly that is isolated, part of a hemihypertrophy syndrome or the result of hamartomatous overgrowth of one cerebral hemisphere.
Human cerebral cortical cell lines from patients with unilateral megalencephaly and Rasmussen's encephalitis.
Ronnett, working with Snyder and three other colleagues, saw an opportunity to break through that research barrier when an 18-month-old girl arrived at Johns Hopkins to undergo surgery for unilateral megalencephaly.