med·ul·lo·blas·to·ma (m d l- -bl -st m , m -d l-)n. A glioma consisting of neoplastic cells that resemble the undifferentiated cells of the primitive neural tube. |
medulloblastoma
[mədul′ōblastō′mə]
Etymology: L, medulla + Gk, blastos, germ, oma, tumor
a poorly differentiated malignant neoplasm composed of tightly packed cells of spongioblastic and neuroblastic lineage. The tumor usually arises in the cerebellum, occurs most frequently at 5 to 9 years of age, and affects more boys than girls. Medulloblastomas are extremely radiosensitive and grow rapidly. The prognosis is poor.
medulloblastoma
a brain tumor composed of medulloblasts.
medulloblastoma
Primitive neuroectodermal tumor Neurology A malignant brain tumor that comprises ±1⁄4 of intracranial tumors in children and adolescents; it is most common at the midline of the cerebellum,
and on the roof of 4th ventricle Clinical Presents with N&V, headache, ataxia, papilledema, nystagmus, irritability, lethargy, cranial nerve palsy, dizziness, altered vision Prognosis 2 yr-survival after relapse is 46% in those
treated with salvage chemotherapy or RT, 0% in untreated Pts. See Brain tumor. Cf Glioblastoma.
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