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mediastinal fibrosis

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fibrosis /fi·bro·sis/ (fi-bro´sis) formation of fibrous tissue.fibrot´ic
congenital hepatic fibrosis  a developmental disorder of the liver marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.
cystic fibrosis , cystic fibrosis of the pancreas a generalized hereditary disorder of infants, children, and young adults, with widespread dysfunction of exocrine glands, signs of chronic pulmonary disease, obstruction of pancreatic ducts by eosinophilic concretions and consequent pancreatic enzyme deficiency, and other symptoms.
endomyocardial fibrosis  idiopathic myocardiopathy seen endemically in parts of Africa and less often in other areas, characterized by cardiomegaly, thickening of the endocardium with dense, white fibrous tissue that often extends to involve the inner third or half of the myocardium, and congestive heart failure.
idiopathic pulmonary fibrosis  chronic inflammation and progessive fibrosis of the pulmonary alveolar walls, with progressive dyspnea and potentially fatal lack of oxygen or right heart failure. The acute form is called Hamman-Rich syndrome.
mediastinal fibrosis  fibrous mediastinitis; development of white, hard fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels.
nodular subepidermal fibrosis 
2. a type of benign fibrous histiocytoma marked by subepidermal formation of fibrous nodules as a result of productive inflammation.
pleural fibrosis  fibrosis of the visceral pleura so that part or all of a lung becomes covered with a thick layer of nonexpansible fibrous tissue; fibrothorax is a more extensive form.

mediastinal fibrosis
n.
The development of fibrous tissue in the upper mediastinum, causing obstruction of the superior vena cava.


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