mechlorethamine hydrochloride

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[mek′lôreth′əmēn]

an antineoplastic alkylating agent. Also called nitrogen mustard.

indications It is prescribed in the treatment of a variety of neoplasms, especially lymphomas, and of malignant effusions.

contraindications Bone marrow depression, pregnancy, infection, or known hypersensitivity to this drug prohibits its use.

adverse effects Among the most serious adverse effects are bone marrow depression and inflammation caused by extravasation at the site of injection. Nausea, vomiting, and alopecia also may occur.

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alkylating agent

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