mecamylamine HCl

mecamylamine HCl

(mek´əmil´əmēn´),
n brand name: Inversine;
drug class: antihypertensive, ganglionic blocker;
action: occupies receptor site, prevents acetylcholine from attaching to postsynaptic nerve endings in autonomic ganglia;
uses: moderate to severe hypertension, malignant hypertension.
References in periodicals archive ?
The active ingredient in Inversine, mecamylamine HCl, is known to modulate nicotinic acetylcholine receptors, a property that Targacept believes holds promise for treating diseases of the central nervous system.
The deal also provides Targacept with exclusive worldwide rights to sell products that exploit patented technology of the University of South Florida relating to the use of mecamylamine HCl for the treatment of neuropsychiatric disorders.
These changes reflect Targacept's product development focus and coincide with its recent acquisition of the marketed product Inversine(R) (mecamylamine HCl) and intellectual property related to mecamylamine HCl from Layton Bioscience, Inc.
A two-year, retrospective, open-label study of the use of mecamylamine HCl to treat patients with Tourette Syndrome (TS) appears today in the summer issue (Vol 10, No.
Mecamylamine HCl, whose brand name is Inversine(R), was developed by Merck and Co.