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mebendazole |
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mebendazole /me·ben·da·zole/ (me-ben´dah-zol) an anthelmintic used against trichuriasis, enterobiasis, ascariasis, and hookworm disease. mebendazole (m n an anthelmintic agent that acts against pathogenic roundworms by inhibiting their glucose intake and secretory processes. mebendazole a broad-spectrum anthelmintic efficient against all gastrointestinal nematodes, lungworms and Moniezia in ruminants. It is not effective against Trichuris spp. and has reduced activity against benzimidazole-resistant worm species. It is not very effective against larval forms of Taenia spp., not effective against Draschia or Habronema spp. in horses, nor against Trichostrongylus axei. It is effective against Strongylus spp., but not against migrating Strongylus vulgaris larvae nor against Trichostrongylus axei, Strongyloides spp. or Anoplocephala perfoliata. It is recommended for general use in horses and combined with metriphonate for use against bot fly larvae. It is useful in dogs but does not remove Echinococcus granulosus or Dipylidium caninum. The drug has very low toxicity but has caused severe acute hepatic necrosis in some dogs. |
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