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measurable disease

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measurable disease
Oncology A condition characterized by a lesion or tumor that can be measured in size, information which is used to evaluate response to treatment. See Occult disease.


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Those with measurable disease only within a previous radiation therapy port must have demonstrated clear evidence of progression prior to study entry.
Our completed Phase I and Phase II clinical trial results show that our lead compound, DAVANAT, when co-administered with 5-Fluorouracil (5-FU), stabilized 43% of end-stage cancer patients with measurable disease from 2 to 13 months.
The findings from this first in human MLN2704 single ascending dose trial indicated the molecule was well tolerated and produced sustained anti-tumor activity, including one patient who achieved a durable partial response in measurable disease for 11 months, as well as a sustained prostate specific antigen (PSA) decline of more than 50 percent.
 
 
 
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