FG-2216 also increased iron and transferrin saturation and hematocrit, hemoglobin, red cell count, reticulocyte count, mean cell volume
and mean cell hemoglobin and restored those parameters to levels not different from unchallenged controls.
Measurement of blood indices: 1 ml of blood was withdrawn from retro-orbital venous plexus from each anesthetized rat into an ethylenediaminetetraacetic acid-containing Eppendorf tube to perform blood indices (red blood cell [RBC] count, hemoglobin concentration [Hb], Hct, mean cell volume
, mean cell Hb [MCH], and MCH concentration).
The complete blood counts [CBC] were analyzed using the automated COULTER (Beckman Coulter], The CBC included haemoglobin [Hb] haematocrit [HCV], total white blood cell count [TWBC], platelet count, mean cell volume
[MCV], mean cell haemoglobin [MCH], mean cell haemoglobin concentration [MCHC] and red cell distribution width [RDW], Serum sodium and potassium were estimated by ABL800 radiometer, by ion selective method, using indirect potentiometry.
There were no significant differences in haematological indices, including haemoglobin concentration, white cell count, mean cell volume
and platelet count, between HIV-negative patients, HIV-positive patients on ART and HIV-positive patients not on ART.
This included Hb estimation, red blood cell count, total leukocyte count, platelet count, packed cell volume (PCV), mean cell volume
(MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW).
Hematologic parameters investigated were total red blood cell count, hemoglobin, packed cell volume, fibrinogen, mean cell volume
, mean cell hemoglobin, mean cell hemoglobin concentration, total white blood cell count, differential white blood cell count, and thrombocyte count.
5), (6) Brittin, et al, demonstrated CBC parameters--including white blood-cell count, red blood-cell count, hemoglobin, hematocrit (Hct), mean cell volume
(MCV), mean cell hemoglobin, and mean cell hemoglobin concentration (MCHC)--are stable in EDTA for at least 24 hours in the refrigerator.
Preliminary studies (see below) have demonstrated a good correlation between RBC-Y and mean cell hemoglobin (MCH), better, in fact, than with mean cell volume
Packed cell volume, butyrylcholinesterase, aspartate aminotransferase, creatine kinase, and creatinine increased with age, whereas albumin, mean cell volume
, calcium, phosphorus, cholesterol, and total solids decreased with age.
2) Mean cell volume
, fL 89 (79-98) Erythrocyte count, [10.
The anaemia is usually normocytic, with normal mean cell volume
(MCV), and normochromic with normal mean cell haemoglobin (MCH), but in 20-50% of patients it is mildly microcytic (reduced MCV) and hypochromic (reduced MCH).
The mean cell volume
(MCV) and mean cell hemoglobin (MCH) are increased, with a mean corpuscular hemoglobin concentration (MCHC) within the reference range.