matrix effect

matrix effect

(1) The difference between the value of an analyte from a fresh patient specimen and from stabilised processed reference materials.
(2) The influence of a sample property—other than the level of the substance or property being measured in the analyte—on a measurement, and thus on the value of the measurand. Matrix effects include physicochemical, mechanistic and analytical interferences, and the presence of isoforms of the substance being measured.
References in periodicals archive ?
Experiments performed for method validation included: limit of detection (LOD), reproducibility of LOD, sample stability, carryover, interference, and matrix effect (ion suppression).
Endogenous compounds like phospholipids in whole blood can produce a matrix effect (22) resulting in suppression or enhancement of ionization (23).
We speculate that this wine matrix effect is a combination of physical and chemical factors including physical sequestration, non-covalent binding of tannins by cell wall components of grape/yeast origin, precipitation and chemical modification resulting in new tannin structures that are not amenable to protein precipitation.
Assay specificity: To evaluate the matrix effect on the ionization of analytes, five different concentration levels of clonidine (0.
The parameters of merit were the limit of detection (LOD) and quantification (LOQ), linearity, recovery and matrix effect, as recommended by ANVISA (2005) and INMETRO (2003).
Thus, evaluation of the most important parameters in geochemical explorations should be done after taking the mineral matrix effect into account.
The interior, mine had Sunny Melon, which is not in tribute to a burlesque legend, seat, door and leather steering wheel inserts along with a matrix effect fascia.
The reason for this is that analyses will pick up components of a sample other than the analyte--a phenomenon known as the matrix effect.
This matrix effect is a thorn in the side of all analytical chemists and contributes to almost all erratic data generated in analytical laboratories.
Although the extent of enhancement was not confirmed quantitatively, the differences in the matrix effect trend indicated a difference between singly charged small molecules and multiply charged biomolecules.
of New York at Stony Brook) makes accessible to English speakers his analysis of the radical historicity of culture and the ideological unconscious, determined by the matrix effect of distinct modes of production, that informs all discursive fields.