toxicity

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toxicity

 [tok-sis´ĭ-te]
the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
developmental toxicity the extent to which a toxin produces adverse effects on a developing embryo or fetus; see also teratogenesis.
maternal toxicity a toxic effect on a pregnant woman or nursing mother, as opposed to one affecting an embryo, fetus, or nursing infant.

tox·ic·i·ty

(tok-sis'i-tē),
The state of being poisonous.

toxicity

/tox·ic·i·ty/ (tok-sis´ĭ-te) the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
O2 toxicity , oxygen toxicity serious, sometimes irreversible, damage to the pulmonary capillary endothelium associated with breathing high partial pressures of oxygen for prolonged periods.

toxicity

(tŏk-sĭs′ĭ-tē)
n. pl. toxici·ties
1. The quality or condition of being toxic.
2. The degree to which a substance is toxic.

toxicity

[toksis′itē]
Etymology: Gk, toxikon
1 the degree to which something is poisonous.
2 a condition that results from exposure to a toxin or to toxic amounts of a substance that does not cause adverse effects in smaller amounts.

toxicity

The sum of adverse effects 2º to exposure to a toxic substance, by mouth, through the skin or respiratory tract. See Amalgam toxicity, Botanical toxicity, Developmental toxicity, Digitalis/digoxin toxicity, Diphtheria toxicity, Excitotoxicity, Hashitoxicosis, Immunologic toxicity, Neurotoxicity, Nickel toxicity, Oxygen toxicity, Reproductive toxicity, Vitamin A toxicity.

tox·ic·i·ty

(tok-sis'i-tē)
The state of being poisonous.

toxicity

The quality or degree of poisonousness.

toxicity,

n the poisonous characteristics of a substance.

tox·ic·i·ty

(tok-sis'i-tē)
State of being poisonous.

toxicity (toksis´itē),

n the ability of a drug or poison to produce harm, especially to cause permanent injury or death. Usually distinguished from
allergenic properties.
toxicity, acute,
n a condition produced after short-term use of a toxic agent. See also dose, lethal, median; dose, lethal, minimum.
toxicity, chronic,
n a condition produced after long-term use of a toxic agent.
toxicity, fluoride,
n See fluoride toxicity.
Enlarge picture
Toxic shock syndrome.

toxicity

the characteristic or quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. See also toxicosis.

toxicity rating
includes slightly toxic (with an oral LD50 in rats of 5000 to 15,000 mg/kg) up to supertoxic (with an LD50 of less than 5 mg/kg).
References in periodicals archive ?
Taking into consideration the greater likelihood of absorption of the drug during the gestational period, particular attention should be paid, when performing the toxicological assays, to the evident clinical signs of maternal toxicity that have resulted in death or a reduction in body weight gain (Calliari-Martin 1998).
Thus, we can say that loss of body mass is one of the main indicators of maternal toxicity (Lyra et al.
These developmental effects are noted at doses below those that cause overt maternal toxicity.
Prior to the monoclonal antibody's approval by the Food and Drug Administration for treating Crohn's disease and rheumatoid arthritis, studies in a mouse model showed no evidence of maternal toxicity, embryotoxicity, or teratogenicity.
200 ppm Maternal toxicity, 100 ppm embyro toxicity, fetotoxity
With earlier CPF treatment (GD9-12), there-was no evidence of general fetutoxicity or alterations of brain cell development at doses up to the threshold for maternal toxicity (5 mg/kg), assessed on GD17 and GD21; however, augmentation of cholinergic synaptic markers was detected at doses as low as 1 mg/kg.

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