mass defect


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mass defect

Chemistry
The difference in the mass of a polyatomic molecule and the sum of the masses of its constituent particles—i.e., electrons, protons and neutrons. The mass defect occurs because matter is converted into energy (as per Einstein’s E = mc2), which is the energy that binds the nucleus together and overcomes the mutual repulsion between protons.

Instrumentation
In mass spectrometry, mass defect refers to the positive or negative difference between an ion’s exact mass and the nearest integer.
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References in periodicals archive ?
The samples were analysed using a Thermo Scientific LTQ Orbitrap XL with an HCD collision cell; the application of mass defect filters was achieved by using the Thermo Scientific MetWorks software package (Figure 2).
The background matrix ions remained because by using only a single MDF to capture all of the metabolites, a relatively wide mass defect range had to be used.
High Resolution LC-MS Based Mass Defect Filter Approach: Basic Concept and Application in Metabolite Detection," in R.
Detection and Characterization of Metabolites in Biological Matrices Using Mass Defect Filtering of Liquid Chromatography/High Resolution Mass Spectrometry Data," Drug Metab.