march hemoglobinuria

hemoglobinuria /he·mo·glo·bin·uria/ (he″mo-glo″bĭ-nu´re-ah) free hemoglobin in the urine.hemoglobinu´ric

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march hemoglobinuria  that seen after prolonged exercise.

paroxysmal cold hemoglobinuria  an autoimmune or postviral disease marked by episodes of hemoglobinemia and hemoglobinuria after exposure to cold, caused by complement-dependent hemolysis due to Donath-Landsteiner antibody.

paroxysmal nocturnal hemoglobinuria  (PNH) a chronic acquired blood cell abnormality with episodes of intravascular hemolysis and venous thrombosis.

toxic hemoglobinuria  that caused by ingestion of a poison.

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march hemoglobinuria

n.

Hemoglobinuria occurring after prolonged or heavy physical exercise.

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march hemoglobinuria,

a rare abnormal condition, characterized by the presence of hemoglobin in the urine, that occurs after strenuous physical exertion or prolonged exercise, such as marching or distance running. See also hemolysis.

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hemoglobinuria [he″mo-glo″bĭ-nu´re-ah]

the presence of free hemoglobin in the urine. adj., adj hemoglobinu´ric.

march hemoglobinuria hemolysis caused by repeated uncushioned shocks or trauma to some body part, such as in some soldiers on long marches, in marathon runners, and in karate practitioners.

paroxysmal cold hemoglobinuria an autoimmune or postviral disease in which there is a biphasic IgG antibody directed against the P blood group antigen. It is marked by episodes of hemoglobinemia and hemoglobinuria after exposure to cold and is detected by the Donath-Landsteiner test. The condition is treated with prednisone and cyclophosphamide and by protection from exposure to cold.

paroxysmal nocturnal hemoglobinuria (PNH) an acquired blood cell abnormality with proliferation of abnormal red blood cells (PNH cells) that are readily hemolyzed by complement, and episodes of severe hemolysis and thrombosis, particularly of the hepatic veins. It is detected by the ham test. Treatment is with androgens or prednisone and, during thrombotic episodes, with heparin.

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march hemoglobinuria

Exertional rhabdomyolysis An episodic hemoglobinuria due to hemolysis caused by repeated mechanical injury to RBCs that travel through small vessels overlying the bones of hands and feet in long-distance marching–soldiers, marathon running, calisthenics, karate Lab Myoglobinuria, proteinuria, ↑ BUN, ↑ enzymes–creatinine phosphokinase, ↑ lactic acid