malonyl CoA

malonyl CoA

first committed intermediate in the synthesis of fatty acids. Inhibitor or carnitine palmitoyl transferase I.
References in periodicals archive ?
He adduced that the low cholesterol could be as a result of slight reduction in lipogenesis brought about by a concomitant reduction in regulatory activities of acetyl-CoA carboxylase, an enzyme which mediates in the rate-limiting step of carboxylation of acetyle CoA to malonyl CoA in fatty acids synthesis.