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malignant transformation

   Also found in: Wikipedia 0.01 sec.
malignant transformation,
the changes that a normal cell undergoes as it becomes a cancerous cell. See also carcinogenesis.

malignant transformation
Oncology The constellation of changes in the growth properties of cells in culture evoked by various agents–eg, radiation, toxins, and viruses that result in development of tumors


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Cyclophilins play a central role in the pathophysiology of chronic viral infection, neurodegenerative diseases and malignant transformation.
The malignant transformation of cells can even be triggered by a very high intensity allergic reaction.
 
 
 
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