malignant spindle cell lesion

malignant spindle cell lesion

An informal or prediagnostic that which may be used among pathologists to slot a malignant tumour and indicate to colleagues the direction of the immunohistochemical workup. MSCLs have a generally worse prognosis if accompanied by necrosis.

Differential diagnosis
Melanoma, sarcomatoid carcinoma, sarcoma (dedifferentiated liposarcoma, MPNST, leiomyosarcoma), malignant GIST, spindle cell mesothelioma.
References in periodicals archive ?
A wide array of both benign and malignant spindle cell lesions can occasionally manifest in oral cavity and present a diagnostic challenge to oral pathologists owing to overlapping histopathological findings.
Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary bladder.
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