malignant lymphoma

lymphoma /lym·pho·ma/ (lim-fo´mah) any neoplastic disorder of lymphoid tissue. Often used to denote malignant l., classifications of which are based on predominant cell type and degree of differentiation; various categories may be subdivided into nodular and diffuse types depending on the predominant pattern of cell arrangement.

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adult T-cell lymphoma , adult T-cell leukemia/lymphoma see under leukemia.

B-cell lymphoma  any in a large group of non-Hodgkin's lymphomas characterized by malignant transformation of the B lymphocytes.

B-cell monocytoid lymphoma  a low-grade lymphoma in which cells resemble those of hairy cell leukemia.

Burkitt's lymphoma  a form of small noncleaved-cell lymphoma, usually occurring in Africa, manifested usually as a large osteolytic lesion in the jaw or as an abdominal mass; Epstein-Barr virus has been implicated as a causative agent.

centrocytic lymphoma  mantle cell l.

convoluted T-cell lymphoma  lymphoblastic lymphoma with markedly convoluted nuclei.

cutaneous T-cell lymphoma  a group of lymphomas exhibiting (1) clonal expansion of malignant T lymphocytes arrested at varying stages of differentiation of cells committed to the series of helper T cells, and (2) malignant infiltration of the skin, which may be the chief or only manifestation of disease.

diffuse lymphoma  in an older classification method, malignant lymphoma in which the neoplastic cells diffusely infiltrate the entire lymph node, without any definite organized pattern.

follicular lymphoma  any of several types of non-Hodgkin's lymphoma in which the lymphomatous cells are clustered into nodules or follicles.

follicular center cell lymphoma  B-cell lymphoma classified by the similarity of the cell size and nuclear characteristics to those of normal follicular center cells; the four previous subtypes are scattered among several types of follicular and diffuse lymphomas.

giant follicular lymphoma  follicular l.

granulomatous lymphoma  Hodgkin's disease.

histiocytic lymphoma  a rare type of non-Hodgkin's lymphoma characterized by the presence of large tumor cells resembling histiocytes morphologically but considered to be of lymphoid origin.

Hodgkin's lymphoma  see under disease.

intermediate lymphocytic lymphoma , lymphocytic lymphoma, intermediately differentiated mantle cell l.

large cell lymphoma  any of several types of lymphoma characterized by the formation of one or more types of malignant large lymphocytes, such as large cleaved or noncleaved follicular center cells, in a diffuse pattern.

large cell, immunoblastic lymphoma  a highly malignant type of non-Hodgkin's lymphoma characterized by large lymphoblasts (B or T lymphoblasts or a mixture) resembling histiocytes and having a diffuse pattern of infiltration.

Lennert's lymphoma  a type of non-Hodgkin's lymphoma with a high content of epithelioid histiocytes and frequently with bone marrow involvement.

lymphoblastic lymphoma  a highly malignant type of non-Hodgkin's lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm.

malignant lymphoma  a group of malignancies characterized by the proliferation of cells native to the lymphoid tissues, i.e., lymphocytes, histiocytes, and their precursors and derivatives; the group is divided into two major clinicopathologic categories: Hodgkin's disease and non-Hodgkin's lymphoma.

mantle cell lymphoma , mantle zone lymphoma a rare form of non-Hodgkin's lymphoma having a usually diffuse pattern with both small lymphocytes and small cleaved cells.

marginal zone lymphoma  a group of related B-cell neoplasms that involve the lymphoid tissues in the marginal zone, the patchy area outside the follicular mantle zone.

mixed lymphocytic-histiocytic lymphoma  non-Hodgkin's lymphoma characterized by a mixed population of cells, the smaller cells resembling lymphocytes and the larger ones histiocytes.

nodular lymphoma  follicular l.

non-Hodgkin's lymphoma  a heterogeneous group of malignant lymphomas, the only common feature being an absence of the giant Reed-Sternberg cells characteristic of Hodgkin's disease.

plasmacytoid lymphocytic lymphoma  a rare variety of small lymphocytic lymphoma in which the predominant cell type is the plasma cell.

primary effusion lymphoma  a B-cell lymphoma associated with human herpesvirus 8 infection, characterized by the occurrence of lymphomatous effusions in body cavities without the presence of a solid tumor.

small B-cell lymphoma  the usual type of small lymphocytic lymphoma, having predominantly B lymphocytes.

small cleaved cell lymphoma  a group of non-Hodgkin's lymphomas characterized by the formation of malignant small cleaved follicular center cells, with either a follicular or diffuse pattern.

small lymphocytic lymphoma  a diffuse form of non-Hodgkin's lymphoma representing the neoplastic proliferation of well-differentiated B lymphocytes, with focal lymph node enlargement or generalized lymphadenopathy and splenomegaly.

small lymphocytic T-cell lymphoma  small lymphocytic lymphoma that has predominantly T lymphocytes.

small noncleaved cell lymphoma  a highly malignant type of non-Hodgkin's lymphoma characterized by the formation of small noncleaved follicular center cells, usually in a diffuse pattern.

T-cell lymphomas  a heterogeneous group of lymphoid neoplasms representing malignant transformation of the T lymphocytes.

U-cell lymphoma , undefined lymphoma a category of non-Hodgkin's lymphomas that cannot be classified into a definite type by either morphologic or known immunocytochemical markers.

undifferentiated lymphoma  small noncleaved cell l.

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malignant lymphoma

n.

See lymphoma.

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malignant

tending to become progressively worse and to result in death; having the properties of anaplasia, invasiveness and metastasis; said of tumors.

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malignant aphtha

see contagious ecthyma.

malignant carbuncle

a form of anthrax in humans.

malignant catarrhal fever (MCF)

an acute highly infectious, fatal herpesvirus disease of cattle, farmed deer and occasionally pigs characterized by an erosive stomatitis and gastroenteritis, erosions on the mucosa of the upper respiratory tract, keratoconjunctivitis, encephalitis, and lymphadenopathy. There are at least two viruses involved. A wildebeest-associated form of the disease is caused by alcephaline herpesvirus 1. It occurs in most African countries in cattle which co-mingle with clinically normal wildebeest and hartebeest. It is epizootic and seasonal. It can also occur in zoological gardens in other countries. Sheep-associated MCF is caused by a poorly characterized virus, presumably ovine herpesvirus 2 (OvHV-2). Cases mostly occur when cattle have had contact with lambing ewes and usually start 1-2 months later. Goats can also act as a source of OvHV-2 infection for cattle. Cases without apparent or recent exposure to sheep do occur but are uncommon. Called also bovine malignant catarrh.

malignant edema

an acute infection of wounds by Clostridium septicum, C. chauvoei, C. perfringens, C. sordellii or C. novyi. The inflammation causes severe swelling and discoloration of skin and exposed tissues. There may be local subcutaneous emphysema and a frothy exudate, depending on the identity of the invading organism. There is a high fever and a profound toxemia; death follows within a few hours if treatment is not provided. Special occurrences are when a large number of animals are affected at one time. These include involvement of the vulva in recently lambed ewes, of shearing or docking wounds, and of the umbilicus or eyes of recently born lambs.

malignant fibrous histiocytoma

a rare aggressive tumor of dogs and cats; composed of densely packed fibroblasts and histiocytes.

malignant head catarrh

see malignant catarrhal fever.

malignant histiocytosis

see malignant histiocytosis.

malignant hyperthermia

see malignant hyperthermia, porcine stress syndrome.

malignant lymphoma

see lymphosarcoma.

malignant pustule

see malignant carbuncle (above).

malignant theileriasis

theileriasis caused by Theileria hirci.

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Patient discussion about malignant lymphoma.

Q. I would like to chat with someone w/any knowledge of fibromyalgia being treated with Methadone my best friend has severe fibromyalgia and has been treated with Methadone for the past several years. She has developed severe chronic anemia in these years. She now has lymphoma. I want to know if she is the only one and if methadone can affect bone marrow.

A. I have never ever heard or read anywhere about methadone causing anemia, nor is that something that an opiate medication would normally cause. We all have a tendency to blame everything that happens to us, health-wise, on methadone sometimes--but in this case, you probably need to look elsewhere for the cause.
the Anemia is probably due to the Lymphoma. if not-her life is out of balance, she might changed her diet and may have shortage of iron or B12.