malate dehydrogenase

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ma·late de·hy·dro·gen·ase (MD),

an enzyme that, using either NAD+ or NADP+, catalyzes the dehydrogenation of malate to oxaloacetate or its decarboxylation to pyruvate and CO2. At least six malate dehydrogenases are known, distinguished by their products, use of NAD+ or NADP+, and specificity of substrate (one acts on d-malate, the rest act on l-malate); one of these proteins is an enzyme in the tricarboxylic acid cycle.

malate dehydrogenase

An oxidoreductase (EC in mitochondria and the cytosol that catalyses the reversible NAD+/NADH reaction in the presence of S-malate, yielding oxaloacetate, a step in the citric acid cycle. Malate dehydrogenase is increased in myocardial infarction, hepatocellular necrosis, megaloblastic anaemia, and cancer.

mal·ate de·hy·dro·gen·ase

(mal'āt dē-hī'drō-jĕ-nās)
Any enzyme that catalyzes the dehydrogenation of malate to oxaloacetate. At least six are known; one is an enzyme in the tricarboxylic acid cycle.
References in periodicals archive ?
mentella: malate dehydrogenase mobility patterns compared with extrinsic gasbladder muscle passages and anal fin ray counts.
Further announcements include the clinical evaluation of glycogen phosphorylase (GPBB), triose-phosphate isomerase (TPI) and malate dehydrogenase (MDH) for possible inclusion in Spectral's novel approach to cardiac diagnostics.
Five proteins that are differentially expressed during differentiation were associated with glucose metabolism: Fructose-biphosphate aldolase A (aldolase A), Alphaenolase (NNE), Malate dehydrogenase (MDH), L-lactate dehydrogenase (LDH) and Glyceraldehyde-3-phosphate dehydrogensae (GAPDH).
Phosphoglycerate kinase, aldolase, pyruvate kinase, NADP-dependent isocitrate dehydrogenase, a-enolase, and malate dehydrogenase are involved in glycolysis or carbohydrate metabolism and are observed to be increased upon death.
IDH), malate dehydrogenase (MDH), malate dehydrogenase ([NADP.