9-13) Data were obtained on primary cancers that had arisen in the oral cavity, larynx/hypopharynx, oropharynx, nasopharynx, major salivary glands
, nose, nasal cavity, and middle ear.
However, they are a rare occurrence in major salivary glands
More than half of these cases involve the major salivary glands
, primarily the parotid glands.
In most cases, these tumors arise in the major salivary glands
Frazell EL Clinical aspects of tumors Of the major salivary glands
Inflammatory disease of major salivary glands
, In: Paparella MM, Shumrick DA.
Approximately 30% of all cases of malignant fibrous histiocytoma of the head and neck involve the sinonasal tract; 15 to 20% involve the craniofacial region; 10 to 15% involve the soft tissue of the neck, the major salivary glands
, and the larynx; and 5 to 15 % involve the oral cavity.
In rare cases, KS affects the major salivary glands
, either as a primary infiltrating neoplasm within the gland parenchyma or as intranodal involvement.
The parotid salivary gland being one of the major salivary glands
of domestic animals contributes to substantial amount of saliva secreted into the mouth.
10,14-16) In veterinary medicine, spontaneous mucoepidermoid carcinomas have been reported in dogs and cats, an African lion (Panthera leo), and an African hedgehog (Atelerix albiventris), most commonly affecting the major salivary glands
The major salivary glands
include parotid glands, submandibular glands and sublingual glands.
They carried out an immunohistochemical study on 37 different tissues from on 28-30 week human fetuses and found positive BPIFA1 expression in all of the major salivary glands