major bleeding event

major bleeding event

Any episode of bleeding, including intracranial haemorrhage and other bleeding that leads to ≥ 5 g/dL (SI, 50 g/L) reduced haemoglobin.
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6) Major Bleeding Event, n (%) 0 (0) Minor Bleeding Event, n (%) 3 (5.
Among patients taking the anticoagulant drug warfarin (Coumadin), obese patients are at much higher risk than non-obese patients of a major bleeding event, according to research presented in May 2015 at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology/ Peripheral Vascular Disease Scientific Sessions.
William Lis, Portola's chief executive officer, said "Andexanet alfa represents a potential important advance to the field of anticoagulation for Factor Xa inhibitor patients who suffer a major bleeding event or those requiring emergency surgery.
Five (0A[cedilla]7%) of 769 patients in the nadroparin group and no patients in the placebo group had a major bleeding event (two-sided p=0A[cedilla]18).
A physician had questioned the practice based on a major bleeding event in one of his patients that he attributed to the quantity and strength of the locking dose.
Development of an agent specifically designed to reverse the activity of Factor Xa inhibitors may provide an antidote for patients who, in rare instances, experience an uncontrolled major bleeding event or require emergency surgery.
The ability to reverse the anticoagulation effect of Eliquis and other Factor Xa inhibitors may be helpful for some patients who experience a major bleeding event or require emergency surgery while onEliquis or another Factor Xa inhibitor.
8%) experienced a major bleeding event as defined by International Society on Thrombosis and Haemostasis criteria.
0), which can triple the risk of a major bleeding event or stroke (CMS, NEJM, Hylek).
Currently, more than 2 million patients are prescribed warfarin in the United States each year, with 1%-5% experiencing a major bleeding event.
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