agglutinin /ag·glu·ti·nin/ (ah-gloo´tĭ-nin)
1. antibody which aggregates a particulate antigen, e.g., bacteria, following combination with the homologous antigen.
2. any substance other than antibody, e.g., lectin, that is capable of agglutinating particles.
anti-Rh agglutinin an agglutinin not normally present in human plasma, which may be produced in Rh− mothers carrying an Rh+ fetus or after transfusion of Rh+ blood into an Rh− patient.
chief agglutinin major a.
cold agglutinin one that acts only at relatively low temperatures (0°–20° C).
group agglutinin one that has a specific action on a particular group of microorganisms.
H agglutinin one that is specific for flagellar antigens of the motile strain of a microorganism.
immune agglutinin any agglutinating antibody.
incomplete agglutinin one that at appropriate concentrations fails to agglutinate the homologous antigen.
leukocyte agglutinin one that is directed against neutrophilic and other leukocytes.
major agglutinin that present at highest titer in an antiserum.
minor agglutinin , partial agglutinin one present in agglutinative serum which acts on organisms and cells that are closely related to the specific antigen, but in a lower dilution.
warm agglutinin an agglutinin more reactive at 37° C than at lower temperatures.
ma·jor agglutinin (m  j r)n. The specific agglutinin present in greatest quantity in an antiserum and developed as a result of immunization. Also called chief agglutinin. |
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