M2 PHARMA-February 28, 2018-CHMP Issues Positive Opinion for Lynparza (olaparib) as Maintenance Therapy
in Platinum-Sensitive Relapsed Ovarian Cancer
Kenilworth, NJ, US (known as MSD outside the US and Canada) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has adopted a positive opinion, recommending a marketing authorisation of Lynparza (olaparib) tablets (300mg twice daily) for use as a maintenance therapy
for patients with platinum-sensitive relapsed high grade, epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete response or partial response to platinum-based chemotherapy.
Rituximab succeeded as a single, long-term maintenance therapy
for patients with severe, difficult-to-treat pemphigus, based on data from a case series of 11 patients.
Roach to conduct a randomized, investigator-sponsored trial comparing active surveillance to SM-88 maintenance therapy
in patients prior to definitive therapy.
Methadone maintenance therapy
was introduced in Kyrgyzstan in 2002.
CHICAGO -- Methadone was associated with a fourfold higher incidence of neonatal abstinence syndrome (NAS), compared with buprenorphine for opioid maintenance therapy
taken during pregnancy, a retrospective study of 204 neonates reveals.
announced today that Eisai has obtained the approval of additional dosage and administration in Japan of the proton pump inhibitor Pariet 5 mg Tablets and 10 mg Tablets (generic name: rabeprazole sodium) to administer 10 mg of rabeprazole sodium per dose twice-daily for the maintenance therapy
of proton pump inhibitor-resistant reflux esophagitis (reflux esophagitis in which it is difficult to achieve satisfactory therapeutic effects by existing treatment with once-daily dosing of proton pump inhibitors).
M2 EQUITYBITES-March 3, 2017-Diplomat reports distribution of REVLIMID for multiple myeloma maintenance therapy
With regard to MM patients after autologous stem cell transplantation, lenalidomide maintenance therapy
significantly improved 3-year PFS rate but did not result in improved 3-year OS rate.
Tapered buprenorphine therapy is far less effective than maintenance therapy
for patients dependent on prescription opioids who seek treatment in the primary care setting, to the extent that it should be used "sparingly, if at all," according to a report published online in JAMA Internal Medicine.
AMSTERDAM -- Twice-weekly proactive maintenance therapy
Long-term maintenance therapy
with retinoids and methotrexate is cost-effective and, for many patients with psoriasis, life changing.