Kinetics of pore formation by an antimicrobial peptide, magainin
2, in phospholipid bilayers.
, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.
2008) and magainins
, a class of peptides from the skin of African clawed frog, Xenopus laevis (Edelstein et al.
En esa investigacion, el equipo dirigido por el doctor Nicholas Nicolaides, del Instituto de medicina molecular de la firma Magainin
Pharmaceuticals en Plymouth Meeting (Pennsylvania), logro aislar en un raton un gen responsable de la hipersensibilidad de los bronquios, considerada como una de las causas del asma.
Using a synthetic version of the substance found in frogs, Magainin
Pharmaceuticals of Plymouth Meeting, Pa.
In the study by Matanic and Castilla (2004), the in vitro antiviral activity of antimicrobial cationic peptides cecropin A, melittin, magainin
I and II, and indolicidin against the arenavirus Junin virus (JV), and herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) was evaluated.
He and his colleagues at Magainin
Pharmaceuticals, a company he founded in Plymouth Meeting, Pa.
His laboratory is now testing magainin
potency against viruses and cancer cells.