magainin


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Related to magainin: protegrin

magainin

A peptide, originally found in the skin of the African clawed frog, which has antimicrobial activity.

magainin

Any of a family of  peptide antibiotics with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis (African clawed frog), which have a broad spectrum of antimicrobial activity against bacteria, fungi, protozoa and viruses. A magainin derivative, pexiganan, is in phase-3 trials for diabetic ulcers.
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Kinetics of pore formation by an antimicrobial peptide, magainin 2, in phospholipid bilayers.
1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.
2008) and magainins, a class of peptides from the skin of African clawed frog, Xenopus laevis (Edelstein et al.
En esa investigacion, el equipo dirigido por el doctor Nicholas Nicolaides, del Instituto de medicina molecular de la firma Magainin Pharmaceuticals en Plymouth Meeting (Pennsylvania), logro aislar en un raton un gen responsable de la hipersensibilidad de los bronquios, considerada como una de las causas del asma.
Using a synthetic version of the substance found in frogs, Magainin Pharmaceuticals of Plymouth Meeting, Pa.
In the study by Matanic and Castilla (2004), the in vitro antiviral activity of antimicrobial cationic peptides cecropin A, melittin, magainin I and II, and indolicidin against the arenavirus Junin virus (JV), and herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) was evaluated.
He and his colleagues at Magainin Pharmaceuticals, a company he founded in Plymouth Meeting, Pa.
His laboratory is now testing magainin potency against viruses and cancer cells.
Jacob co-founded Magainin Pharmaceuticals and served as its COO until 1996.
Nicolaides was the Director of Research at Magainin Pharmaceuticals, where his research focused on the development of bio-therapeutics to treat respiratory disease.
Horvitz's first biotech company was Magainin Pharmaceuticals Inc.
Dougherty held senior positions with Magainin Pharmaceuticals, Inc.