mafenide


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mafenide

 [maf´en-īd]
a compound used in the form of the acetate and hydrochloride salts for topical treatment of infections.

mafenide

/maf·en·ide/ (maf´in-īd) an antibacterial, used topically as the monoacetate salt in superficial infections.

mafenide

a sulfonamide that is not inhibited by the presence of pus and necrotic tissue; used mostly for local application to infected wounds. Called also homosulfanilamide, sulfamylon.
References in periodicals archive ?
The wound was cleansed, hemostasis obtained, and the wound was dressed with gauze dressings soaked in 5% solution of mafenide acetate (Sulfamyalon).
Topical 5 percent mafenide acetate solution (5% Sulfamylon Solution) was found to be bactericidal against many nosocomial Acinetobacter isolates, and wound-care protocols suggest its use in place of normal saline for washing wounds [21].
Off-label drug use in WOC nursing: Issues related to use of mafenide acetate to treat infected chronic wounds.
Limited success has also been seen with non-antibiotic remedies such as chlorohexidine, nitrofurazone, PVP-I, mafenide and mupirocin.
Cutaneous burns, when they do occur should be treated as thermal cutaneous burns with bacitracin, silver sulfadiazine or mafenide acetate.
The in vitro study compared Acticoat dressings to three conventional antimicrobial burn wound treatments: silver nitrate, mafenide acetate and silver sulfadiazine.