macroprolactinoma

macroprolactinoma

/mac·ro·pro·lac·ti·no·ma/ (-pro-lak″tĭ-no´mah) a prolactinoma more than 10 mm in diameter, usually associated with serum prolactin levels above 500 ng per mL.

macroprolactinoma

[-prōlak′tinō′mə]
a prolactin-secreting pituitary tumor more than 10 mm in diameter that causes serum prolactin levels higher than 500 ng/mL. Bromocriptine is used with some success to shrink tumor size before surgery. Frequent monitoring of endocrine status is indicated for the remainder of the patient's life after therapy.
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The diagnosis was primary hyperparathyroidism in association with macroprolactinoma.
Treatment of macroprolactinoma with cabergoline: a study of 85 patients.
Symptoms and signs at the time of presentation in patients with macroprolactinomas Symptoms No of patients (%) Headache 15 (100) Loss of libido 15 (100) Visual symptoms 13 (86) Erectile dysfunctions 10 (67) Gynaecomastia 7 (47) Galactorrhoea 3 (20) Decreased shaving frequency 3 (20) Infertility 3 (20) Arrested puberty 1 (7) Table II.
Therefore, this study was planned to assess eficacy and safety of rapid escalation of cabergoline doses in men with macroprolactinomas.
Study design: Fifteen consecutive men with macroprolactinomas attending the Endocrine Clinic of the Nehru Hospital at Postgraduate Institute of Medical Education and Research, Chandigarh, India, during September 2004 to June 2006 were recruited for the study.
Selection criteria: Post-pubertal men with macroprolactinomas (any tumour diameter > 10 mm) and serum prolactin level > 150 [micro]/l were recruited.
The dose escalation of cabergoline in patients with macroprolactinomas in previous studies had varied from monthly to two monthly.
Spinal epidural lipomatosis associated with pituitary macroprolactinoma.
Adipsic diabetes insipidus following pituitary surgery for a macroprolactinoma.
There are case series and case reports in the literature about patients who have been operated for craniopharyngioma (18-20) and one case for macroprolactinoma (21) who have developed adipsic DI.
High prolactin levels may be missed by immunoradiometric assay in patients with macroprolactinomas.
Barnett PS; Palazidou: Treatment of macroprolactinomas with quinagolide (versus bromocriptine).