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macroamylase

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macroamylase /mac·ro·am·y·lase/ (-am´ĭ-lās) a complex in which normal serum amylase is bound to a variety of specific binding proteins, forming a complex too large for renal excretion.
mac·ro·am·y·lase (mkr-m-ls, -lz)
n.
A serum amylase in which the enzyme is present as a complex joined to a globulin, resulting in a complex that has a high molecular weight that inhibits its renal excretion.

macroamylase
[-am′ilās]
a form of serum amylase in which the enzyme is bound to a globulin. Because the resulting complex is too large for renal clearance, plasma amylase levels are increased. The elevated amylase level may not be harmful but may be diagnostic of other disorders, such as pancreatitis or biliary tract disease.

macroamylase [mak″ro-am´ĭ-lās]
a complex in which normal serum amylase is bound to a variety of specific binding proteins, forming a complex too large for renal excretion. It is not correlated with any specific disease state; however, in hyperamylasemia or pancreatitis, it can result in urinary amylase levels not rising concomitantly with serum levels.

macroamylase
a complex in which normal serum amylase is bound to a variety of specific binding proteins, forming a complex too large for renal excretion. It is not correlated with any specific disease state; however, in hyperamylasemia or pancreatitis, it can result in urinary amylase levels not rising concomitantly with serum levels.


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The diagnosis of macrolipasemia was not pursued because <2% of the activity in the supernatant was lost (decreasing from 15 268 to 14 960 U/L) after precipitation with polyethylene glycol as described for macroamylase screening [4].
 
 
 
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