mRNA


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Related to mRNA: tRNA, rRNA

mRNA

 
messenger RNA; see ribonucleic acid.

mRNA

Abbreviation for messenger RNA. See entries under ribonucleic acid

mRNA

messenger RNA.

mRNA

abbr.
messenger RNA

mRNA

abbreviation for messenger RNA.

messenger RNA

An RNA (ribonucleic acid) molecule which has coding regions and translation signals derived from a gene, carries the reverse template message from DNA, and is required for protein synthesis. mRNA is a nucleic acid intermediate that specifies the amino acid sequence of a polypeptide during translation. Under most circumstances, and in accordance with the so-called central dogma of biology, the message flows from DNA to RNA, which is then translated into protein. DNA is wrapped around proteins (histones in chromatin); the DNA then unwinds, allowing transcription by one of the three RNA polymerases, forming a primary (nuclear) RNA transcript that is then processed to remove the intervening RNA sequences (introns), yielding a mature mRNA molecule. The mature mRNA then passes through nuclear pores into the cytoplasm, where translation into proteins occurs. When a particular mRNA is no longer needed, it is degraded by ribonucleases.

mRNA

Abbreviation for messenger RNA.

mRNA

see MESSENGER RNA.

mRNA

messenger ribonucleic acid

mRNA

a unique set of tRNAs, mRNAs, rRNAs, transcribed from mitochondrial DNA by a mitochondrial-specific RNA polymerase, which account for about 4% of the total cell RNA which is transcribed.
References in periodicals archive ?
The Company is utilizing its proprietary mRNA Technology Platform, which offers the ability to deliver messenger RNA therapeutics predictably to selected tissues in vivo, thereby unlocking the value of mRNA as a new therapeutic modality.
Moderna's mRNA Therapeutics(TM) platform builds on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs with therapeutic activity inside and outside of cells.
3A-C, in which the baseline expression of plasma EMV mRNA became undetectable (Ct, >32) just before HSCT and increased after HSCT.
Other cells produced mRNAs related to gliding and twitching, providing strong evidence that cells in deep sediments are capable of a variety of locomotion.
Quantitative standards for the real-time HBoV1 mRNA PCR were made by cloning a plasmid (pCR4-TOPO; Life Technologies Corp.
In cell E6, E7 mRNA quantification was performed by resuspending the cells in hybridization mixture and a cocktail of oligonucleotide probes (HPV OncoTect; IncellDx).
Preoperative TSHR mRNA greater than 1 ng/mcg as a sole predictor of cancer had a positive predictive value (PPV) of 81% and specificity of 83% in 374 patients with surgically confirmed pathology, Dr.
To examine the distribution of GLUT4 in different porcine tissues, we detected the mRNA expression in heart, liver, skeletal muscle, brain, lung, kidney and intestine by Real-time RT-PCR.
Another important issue is how to bring the siRNA molecules into the target cells so that they can interact with the target mRNA.
The treated groups had higher levels of both MMP-2 mRNA and protein activity than did the control group, although there was a decline in the high-dose group (Figure 1D,E).
After the volunteers provided saliva samples, the researchers examined the approximately 3,000 different mRNA segments present, looking for distinct differences between the two groups of volunteers.