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Lysyl oxidase

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.01 sec.
Lysyl oxidase
An enzyme required for the crosslinking of elastin and collagen molecules to form properly functioning connective tissue; present in relatively low levels in at least some forms of cutis laxa.
Mentioned in: Cutis Laxa

lysyl oxidase
a copper-containing enzyme responsible for the maintenance of collagen and elastin in tissues; its absence leads to aneurysm formation in and rupture of large blood vessels.


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The enzyme called lysyl oxidase (LOX) has been found to stiffen collagen, a major component of the supportive tissue in the breast.
The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase.
The lysyl oxidases lysyl oxidase (LOX) and (LOXL) are responsible for elastin cross-linking.
 
 
 
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