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lysosome

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lysosome /ly·so·some/ (li´so-sōm) one of the minute bodies occurring in many types of cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion.lysoso´mal
secondary lysosome  one that has fused with a phagosome (or pinosome), bringing hydrolases in contact with the ingested material and resulting in digestion of the material.

ly·so·some (ls-sm)
n.
A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion.

lyso·somal adj.

Lysosome
Membrane-enclosed compartment in cells, containing many hydrolytic enzymes; where large molecules and cellular components are broken down.
Mentioned in: Mucopolysaccharidoses

lysosome
[lī′səsōm]
Etymology: Gk, lysein + soma, body
a cytoplasmic, membrane-bound particle that contains hydrolytic enzymes that function in intracellular digestive processes. The organelles are found in most cells but are particularly prominent in leukocytes and the cells of the liver and kidney. If the hydrolytic enzymes are released into the cytoplasm, they cause self-digestion of the cell. Thus lysosomes may play an important role in certain self-destructive diseases characterized by the wasting of tissue, such as muscular dystrophy.

lysosome [li´so-sōm]
one of the minute bodies occurring in many types of cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion. adj., adj lysoso´mal.

lysosome
a small intracellular organelle occurring in the cytoplasm of most cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion. Lysosomes are particularly prominent in certain cells such as granulocytes, in which they are the granules, and activated macrophages. They play a major role in intracellular killing of microorganisms, destruction of foreign or damaged tissues, and in embryogenesis.


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Proteins are classified, according to their subcellular locations, into the following 18 groups: cell wall, centriole, chloroplast, cyanelle, cytoplasm, cytoskeleton, endoplasmic reticulum, extracell, Golgi apparatus, hydrogenosome, lysosome, mitochondria, nucleus, peroxisome, plasma membrane, plastid, spindle pole body, and vacuole [22].
The key idea is that we appear to have overcome the transport defect in the lysosome that is brought about by the genetic defect or mutation.
The key idea is that we appear to have overcome the transport defect in the lysosome that is brought about by the genetic defect or mutation," said Dietschy, who has studied cholesterol metabolism for almost 50 years.
 
 
 
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