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lysosome |
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lysosome /ly·so·some/ (li´so-sōm) one of the minute bodies occurring in many types of cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion.lysoso´mal secondary lysosome one that has fused with a phagosome (or pinosome), bringing hydrolases in contact with the ingested material and resulting in digestion of the material.
Lysosome Membrane-enclosed compartment in cells, containing many hydrolytic enzymes; where large molecules and cellular components are broken down. Mentioned in: Mucopolysaccharidoses lysosome [lī′səsōm] Etymology: Gk, lysein + soma, body a cytoplasmic, membrane-bound particle that contains hydrolytic enzymes that function in intracellular digestive processes. The organelles are found in most cells but are particularly prominent in leukocytes and the cells of the liver and kidney. If the hydrolytic enzymes are released into the cytoplasm, they cause self-digestion of the cell. Thus lysosomes may play an important role in certain self-destructive diseases characterized by the wasting of tissue, such as muscular dystrophy. lysosome a small intracellular organelle occurring in the cytoplasm of most cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion. Lysosomes are particularly prominent in certain cells such as granulocytes, in which they are the granules, and activated macrophages. They play a major role in intracellular killing of microorganisms, destruction of foreign or damaged tissues, and in embryogenesis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Hemocytic lysosome response in the snail Helix aspersa after exposure to the fungicide copper oxychloride. The researchers posit that nerve cells hungry for choline compounds raid their own cell membranes for phosphatidylcholine; this leaves holes on the underside of the membrane and possibly exposes portions of APP to marauding lysosomes. Given that during synthesis of the C/Fe particulates, the material is subjected to extreme acidification procedures, the acidification reached in a lysosome would not be sufficient to decompose the particle. |
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