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lysosomal |
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lysosomal pertaining to or emanating from lysosomes. lysosomal enzymes enzymes located in the lysosomes. lysosomal phospholipidosis overloading of lysosomes with phospholipids as caused by the inhibition of phospholipidases by aminoglycosides. lysosomal storage diseases diseases in which there is a congenital or acquired deficiency of an enzyme so that one or more specific metabolic processes are not completed. As a result there is an accumulation of metabolic products in the cellular lysosomes. The histological lesion indicates the error in function but not the cause. Most of these diseases are inherited but swainsonine poisoning is caused by plant (Swainsona, Astragalus, Trachyandra spp.) poisoning. See also ceroid lipofuscinosis, glycogenosis, glycoproteinosis, lipid storage disease, mucopolysaccharidosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Anderson-Fabry disease is a lysosomal storage disorder caused by congenitally lysosomal destabilizatiun), and loss of DNA integrity. Dapsone (4,4' diaminodiphenylsulfone) inhibits neutrophil migration and endothelial attachment, and it blocks neutrophil secretion of lysosomal enzymes. |
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